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Continuous therapy of obese people or patients with overweight, including people having associated with adiposity risk factors, in a combination with moderate hypo caloric diet. The inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides.It is not recommended to use Euslim if you: are allergic to any ingredient in Euslim; constantly have problems absorbing food (chronic malabsorption); have gallbladder problems; have cholestasis (a problem of bile flow from the liver to the intestines);Bowel movement urgency; gas with discharge; inability to control bowel movements; increased number of bowel movements; oily discharge; oily or fatty stools; oily spotting. Cyclosporine should be taken at least 2 hours before or after orlistat to ensure maximum absorption of cyclosporine into the bloodstream. It exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipases. As undigested triglycerides are not absorbed, the resulting caloric deficit may have a positive effect on weight control. In a combination with hypoglycemic medicines (Metformin, Sulfonylurea drugs and/or insulin) or with moderate hypo caloric diet in patents having 2 type of diabetes and overweight or adiposity.Other serious side effects: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent stomach pain.Euslim is a reversible inhibitor of lipases.Side effects, including risk of bleeding may be increased if taking anticoagulants simultaneously with Orlistat.Euslim may seriously decrease Cyclosporine's effectiveness. Euslim is used together with a reduced-calorie diet and weight maintenance to treat obesity in people with certain risk factors (such as diabetes, high blood pressure, and high cholesterol or triglycerides). Systemic absorption of Euslim is therefore not needed for activity.
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